Difficulty of LS engine swap in a 89 Suburban?

So this isn’t your typical “will it fit?” Question. I know it will fit, but I would like to know what is the difficulty of making one work? My friend is an old school mechanic but is not opposed to fuel injection. 

His Suburban is an ‘89 4x4. It has a 350 in it. He’s talking about putting a Cadillac 472 in it with a TBI retrofit, because he wants more power and torque to tow with (which he does all the time). 

I had the idea of him putting a 6.0L LS motor in it, but he’s concerned about the ease of making everything work. He’s keeping the rest of the drivetrain, so it would have to work with that. 

I know there’s all sorts of stuff out there to make this work, but I don’t even know where to start. 

It already has a fuel injection fuel system so a pump swap and adaptation of the lines is all it takes there.  Wiring can be done via standalone or modifying a harness.  Radiator hoses for newer truck will hook him up to factory radiator and removing a 4” long adapter tube from the power steering pump will let him use his stock lines.  It’s about the simplest ls swap one can do.  Way easier than making tbi work on a 472.  Aftermarket flywheel with torque converter bushing will bolt it to whatever transmission he has(if auto) and motor mount adapters will drop it on factory mounts.  99+ truck exhaust manifolds fit the 73-87 chassis 

With a msd box and a carb manifold he might even be able to use the tbi from whatever is in there on the ls motor.  Figure out distributor input pulses to the ecu, a plate for the throttle body to manifold,  and the right size injectors/ fuel pressure and it would probably run.

 

With a msd box and a carb manifold he might even be able to use the tbi from whatever is in there on the ls motor.  Figure out distributor input pulses to the ecu

LS doesn't have any provision for a distributor. There does exist an MSD box to run the LS coils based on a few simple inputs and run a carb manifold (or totally non-integrated separate fuel controls of your choice), but it's not any cheaper of an option than several of the other ones.  

If he's not looking for the cheapest route, but would prefer guaranteed success, a friend of mine just got an engine from http://bdturnkeyengines.com.  he got a video of his engine being run on a Dyno and the wiring harness and computer are already setup.