We've been doing the camper + enclosed trailer for a couple of years.
I researched a bunch of options, with the primary goal of being able to transport a car in an enclosed trailer, and also having living quarters. Didn't want a motorhome (extra registration/insurance/maintenance) when I already have a pickup. Most 5th wheel 'toy haulers' aren't rated high enough even for a Miata, and have high ride heights making for steep ramps. Gooseneck race haulers with living quarters are pricey, and looong...
We ended up with a Lance 981, and a 24' enclosed trailer. The Lance has a slide, and while heavy, provides plenty of living space for our use. I went long on the trailer, so I could load a motorcycle in front of the car, while still having room for a workbench. It's worked very well for us.
DSC_9813 by Rodan AZ, on Flickr
We've taken several trips where we just hit an RV park and use that as a base camp for a few days, and unload the car to enjoy ourselves. Utah, the Black Hills, etc. We've also used it to trave to motorsports events... the only problem is we can only haul one car. In the rare cases we take two, my wife has to follow in the other car.
DSC_0645 by Rodan AZ, on Flickr
IMHO, a full ton dually is just about required. Anything less, and you'll be tapped out unless you have a very small camper. The Torklift Superhitch and Supertruss are about the only way to carry any significant tongue weight with an extention, which again will be a requirement unless it's a small camper. I've also used the Torklift Stableloads with great success. A Hellwig Big Wig sway bar is also a good investment. Don't believe the brochure weights for a camper. Make sure you're getting an actual weight as equipped. Our camper is significantly heavier than the brochure weight.
We started having some engine issues with our first dually last summer and upgraded to a newer truck. Big investment, but the improvements in suspension, power and transmissions make for effortless driving compared to the old rig.
MRLSTruck2 by Rodan AZ, on Flickr
The 'trailer toad' may help you get away with a non-dually, but honestly, I wouldn't haul our camper without a dually. Much less tow something behind. Interestingly, a friend of mine 'invented' the trailer toad. They're pretty cool, but not cheap!
All in all, IMHO the camper + trailer is the most flexible combo out there. You have a truck for truck stuff, and can haul just the trailer for local events. Throw on the camper for further events where you want to stay at the track, or for vacations. Getting out to the boonies for some hiking... just take the truck/camper.