New Tires for Towing Van

Jean Claude VanAirDamme (2013 Express 3500) needs new tires... ones on it are from 2017 and showing some signs of sidewall cracking...

Looking for E load rating 

Highway mileage is a priority

It will not be going offroad, nor is snow traction a factor

Currently looking at the following, but totally open to other/better options:

BRIDGESTONE DUELER H/T 685

BRIDGESTONE DUELER LX

MICHELIN AGILIS CROSSCLIMATE

MICHELIN AGILIS LTX

HANKOOK DYNAPRO HT RH12

I have a 2006 Express 2500 with Cooper Discoverer AT3. And I like them a lot. I work for a forklift company and we use them on nearly all the service vans. My current work van is a 2020 Express 2500.  They wear good and don't produce a lot of road noise. Either way from my house I have a small hill to get to the main road and I have never had any trouble with snow or wet conditions. 

Really liking my general grabber hts I got on my tow rig right now.

Worked for Michelin for a short bit. Found out two things. 
1) why their tires cost more... they really do make a better tire. 
2) absolutely HORRIBLE company to work for 

I have run older versions of all of you list. And all are better than several I've had not on your list. 
But the Michelin Defenders were WAY better. 
I hear that commercial folks like the AGILIS  better than the Defenders. 
If you KNOW you are keeping it, prolly worth the extra coin. 
YMMV

In reply to 03Panther :

thank you sir!

the defender isn't even made in my size anymore (245/75-16, e load)... 

Any thoughts on the michelin ltx m/s2?

Not positive, but I think the ltx m/s2 is the newest defender. 
We sprung for the good tires on my wife's 2011 truck, and loved them. Truck was wrecked before total miles could be determined, but they were wearing fantastic, road great, and great traction. 
Later, while working for Michelin, needed tires for the Highlander; even with the company discount, I still couldn't afford 'em!

The ltx even though a "hwy" tread, still has great traction for a 4x4. The AGILISis supposed to be the ultimate hwy tire!

I had the LTX on both of my conversion vans.  They gave me absolutely zero problems.  Great in snow, great in the rain, perfectly solid when towing, and they lasted forever - somewhere around 70k miles.  The only thing I don't like about them is that initial cost, but I guess they're expensive because they're worth it.

In reply to wae :

Part of me is scared to buy top teir tires (say that fast!) on anything... every time I do, something happens and I I don't get the long term advantage 

well i mixed up my sizes... the only decent looking ones are the bridgestone dueler lx, michielin agilis crossclimate (which has way more snow traction than i need), michelin agilis ltx (which is a single size only, oem tire)

I had general grabber hts on a couple f250s and really liked them- towed very well and were long lasting. I've also had good success with the ltx- but towed less with it. Quiet tire though. 

Some people automatically hate cheap Asian tires but I am very happy with the Sailun Terramax on my '21 Tundra.  They get really good reviews and Sailun is highly respected in the trailer tire world.  Made in Cambodia.  No idea how they'll hold up over time.  

I have been running the Cooper E rated tires on my E350 van.  I've been very happy with them.  Almost every day I'm pulling one of our 5 trailers.

I had cooper HT3s in that 245/75r16 size on the suburban 2500. highway version of the AT3 that everyone seems to love. they worked well, lasted a long time, and got good mileage. Traction overall was very average.  Ride quality improved with a move to AT tires (Vredstein Pinzas), but lost a lot of steering precision and about 1 mpg. 

Michelin LTXs have always served me very well in the past as well. Personally I'd pick them over the HT3s if the size is available. 

My F-250 came with Michelin LTX A/T 2 (not agilis), and I would definitely buy them again.  Tire Rack says they have them in 245/75R16.