I just bought some Duluth undies. I got the ones that are 3% spandex and 97% cotton. I love them.
I'm convinced that the clothing on the market today that says "moisture wicking" is for people who sweat half a teaspoon of sweat per day. Nylon, polyester, and acrylic do not wick away moisture. They feel like a trash bag against my skin. I don't care how "micro" the fiber is, it feels like synthetic fabric and I hate it.
Therefore I didn't get the "buck naked" undies since they were entirely synthetic. I got the 3/97 spandex cotton ones and I love them.
On a side note, I also got a pair of the firehose stretch pants. 
Love love love them.
